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so apart from this
apart from all these european databases
that we discussed there's one more you
know remember i told you earlier that
one such example is ebi
ebi european bioinformatics institute
and this name
is you know something like
very very important in terms of
bioinformatics tools to name ebi and
ncbi ebis european bioinformatics
institute and ncbi is national center of
biotechnology information
both are playing the crucial role
in maintaining a huge amount of data in
all the different kinds of database so
european biological or european
bioinformatics institute
under
it is under embl
okay what is embl full form european
molecular biology laboratory embl
they provide
the bioinformatics information it's
actually very important that we have a
lab facility
which is wet lab facility of course and
then we have this dry lab facility so
what is the difference between the
wetland dry lab and cross flow let's
understand we have weight lab where we
run all the experiment experiments are
done experiments on
on dna rna
experiments on protein all these things
we perform we do
and then all the data that we gather
is transferred to the dry lab where we
store the data
we analyze the data
we modify
the data
and we cross talk or cross check
cross
check
sorry cross check after
after what cross check after
modification after
uh
prediction so we do prediction here
of course we do prediction and we cross
check that prediction and then based on
that we get a yes
or no or not up or no based on that we
can understand
an organism and how that organism
behaves because now basically it's not
likely you know there are plenty of
years earlier when we see an organism
based on its morphology and appearance
we decide everything but nowadays we
don't even look at morphology it doesn't
matter whether how much similar they
look from outside phenotype doesn't
matter everything that matter is the
genotype
how it's actually made up and everything
is possible with this crosstalk of
weight lab and dry lab so that's why
this always the greatest uh
biotechnology greatest bioinformatics
tools can only be
hosted
they are connected
to molecular lab or weight lab facility
so for example here is the european
molecular biology laboratory embl under
this we run the experiment on all and
that hosts in the ebi okay it was
established in 1980s
okay
at embl okay and it was first as a
nucleotide sequence database it started
as a nucleotide sequence database and
then sooner it manages start managing
different kinds of biological databases
and now what we have we have dna
sequences genome sequences we have
microarrays proteomics structural
genomics
and so many different things are under
this rule and basically when he's heard
this name you know genomics proteomics
structural genomics
all this sounds very complicated all
this sounds very you know similar so
people use this terms quite often so for
that also i'll do a myth buster portion
at the end of this lecture which will
help you to understand and forget all
the misconception and understand only
what is real okay
so
always we have uh
we need a need we require a need
to collect
store
and curate
all the little bit of information from
genome proteome
structure of the protein and all the
different places and put them together
okay and we have multiple genome
projects running uh in different places
of the earth okay and the data came in
so we'll gather them okay so what
happened in 1992
embl voted to establish this ebi
and then the zbi got established
embl started then and the ebl got
established 1992 okay so basically
it provides
the search
assisted to lead by informatic
revolution that is what
ebi is actually made for
and now ebi
hosts
various databases
various it actually let me write it
hosts
various
various
databases
okay
so this various database what kind of
database it can be it can be nucleotide
database
right
it can be
microarray
microarray database
it can be
pathways protein pathways
okay there are different pathways
available that database
uh protein
structural database
all these different types of database
hosted under
this ebi and there are various tools
available as well there are various
tools available there actually
there's various tools that will help us
to find out information regarding all
these different
type
from different type of database like
nucleotide sequence microarray pathways
proteins sequence and protein structure
okay so for example let me write down
important name of the tool one of them
is
you