Bioinformatics databases | Bioinformatics lecture 1

 

we say databases databases

based on this type what we have we have

a

sequence

database we have

structural

database right

apart from that we also have two more

types of database here which we will

discuss now

we have family for protein we have

family

and domain

remember in case of protein we have

family and domain database

and we also need interaction

interaction database

okay

so you can see that

throughout this process of

lecturing uh for bioinformatics i'll use

database terms so many times and i'll

classify database in so many different

ways i'll also sum it up later on

but for now understand this for for a

protein database here we are talking

about for a protein database we have

sequence database structural database we

have talked about it a little bit

earlier

and now i am also going to talk about

the family and domain database and

interaction database because

if there is a protein x and there's a

protein y

then the protein x will interact with

protein y

this protein protein interaction

is very important and this protein

protein interaction

need to be

analyzed with the interaction databases

but family and domain database is a

place where protein family so what is

the this database example of what let me

write it down

pro site

prosite is an example

of this family and domain database

right

so what it has it has different

structural pattern

if we run the profile of the structural

pattern what we'll find out we can find

out different family of proteins

okay families of protein and domain of

the proteins because we know that when

the protein structure is being formed ah

there are different domain structures

domain of the proteins are you know

after super secondary structures we have

these domains where they have a

particular role to play okay so remember

when you try to understand

bioinformatics tools of bioinformatics

particularly for a protein database

and protein database search you need to

have a clear understanding of protein

topology and how exactly the protein

structure is formed from primary

secondary tertiary and all okay it's

very very important what is domain what

is motive

all these ideas must be crystal clear

otherwise you cannot understand and i

will not explain what is domain and

motive right here because this is a

class of bioinformatics

and we have interaction database

okay example for such interaction

databases swiss 2d swiss

two-dimensional gel

so this dimensional gel

page

what is page poly acrylic gel

you

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